Mammography, Treatment Improvements Have Prevented 483,000 Breast Cancer Deaths In The U.S. Since Just 1989

Screening mammography for the detection of breast cancer became widely available in the mid-1980s and there have been numerous advances in effective therapies in the last 30 years. To estimate the number of breast cancer deaths averted due to the collective effects of screening mammography and improved treatment, R. Edward Hendrick, PhD, of the University of Colorado School of Medicine, Jay Baker, MD, of Duke University Medical Center, and Mark Helvie, MD, of the University of Michigan Health System, analyzed breast cancer mortality data and female population data for U.S. women aged 40 to 84 years over the past three decades.

Cumulative breast cancer deaths averted from 1990 to 2015 ranged from more than 305,000 women to more than 483,000 women depending on different background mortality assumptions. When extrapolating results to 2018, cumulative breast cancer deaths averted since 1989 ranged from 384,000 to 614,500. When considering 2018 alone, an estimated 27,083 to 45,726 breast cancer deaths were averted. The investigators calculated that mammography and improved treatment decreased the expected mortality rate of breast cancer in 2018 by 45.3 to 58.3 percent.

"Recent reviews of mammography screening have focused media attention on some of the risks of mammography screening, such as call-backs for additional imaging and breast biopsies, downplaying the most important aspect of screening--that finding and treating breast cancer early saves women's lives. Our study provides evidence of just how effective the combination of early detection and modern breast cancer treatment have been in averting breast cancer deaths," said Dr. Hendrick.

It could get even better, since only about half of U.S. women over 40 years of age receive regular screening mammography. "The best possible long-term effect of our findings would be to help women recognize that early detection and modern, personalized breast cancer treatment saves lives and to encourage more women to get screened annually starting at age 40."

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